Scores
Each row corresponds to a position in the reference protein. Below each position is the fraction of sequences that contain one of the basic amino acids. A low fraction indicates the position is either severely gapped or unalignable and has little information. Expect poor prediction at these positions.
Each column corresponds to one of the twenty amino acids.
Each entry contains the score at a particular position (row) for an amino acid substitution (column). Substitutions predicted to be intolerant are highlighted in red.
pos |
A |
C |
D |
E |
F |
G |
H |
I |
K |
L |
M |
N |
P |
Q |
R |
S |
T |
V |
W |
Y |
1P 0.85 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
2Q 0.95 |
0.01
|
0.00
|
0.02
|
0.41 |
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.00
|
0.01
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
3I 0.95 |
0.03
|
0.01
|
0.01
|
0.01
|
0.77 |
0.01
|
0.01
|
1.00 |
0.01
|
0.71 |
0.08 |
0.01
|
0.01
|
0.01
|
0.01
|
0.02
|
0.03
|
0.32 |
0.03
|
0.25 |
|
4T 0.95 |
0.09 |
0.02
|
0.04
|
0.02
|
0.01
|
0.03
|
0.01
|
0.02
|
0.03
|
0.02
|
0.01
|
0.06 |
0.35 |
0.03
|
0.02
|
0.97 |
1.00 |
0.04
|
0.01
|
0.01
|
|
5L 0.95 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
6W 0.95 |
0.03
|
0.00
|
0.01
|
0.01
|
0.03
|
0.03
|
0.00
|
0.01
|
0.01
|
0.01
|
0.00
|
0.01
|
0.01
|
0.01
|
0.01
|
0.12 |
0.02
|
0.01
|
1.00 |
0.02
|
|
7Q 0.95 |
0.02
|
0.00
|
0.00
|
0.02
|
0.00
|
0.01
|
0.02
|
0.01
|
0.60 |
0.02
|
0.01
|
0.02
|
0.01
|
0.91 |
1.00 |
0.01
|
0.02
|
0.01
|
0.00
|
0.01
|
|
8R 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
9P 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
10L 1.00 |
0.01
|
0.00
|
0.00
|
0.00
|
0.03
|
0.01
|
0.00
|
0.80 |
0.01
|
1.00 |
0.15 |
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.01
|
0.87 |
0.00
|
0.01
|
|
11V 1.00 |
0.12 |
0.02
|
0.02
|
0.17 |
0.02
|
0.04
|
0.04
|
0.17 |
0.47 |
0.11 |
0.03
|
0.05 |
0.05 |
0.12 |
0.32 |
0.05 |
0.10 |
1.00 |
0.01
|
0.03
|
|
12T 1.00 |
0.17 |
0.01
|
0.10 |
0.32 |
0.02
|
0.08 |
0.07 |
0.05
|
0.54 |
0.09 |
0.03
|
0.11 |
0.13 |
0.21 |
0.59 |
0.15 |
1.00 |
0.07 |
0.01
|
0.03
|
|
13I 1.00 |
0.67 |
0.10 |
0.01
|
0.02
|
0.01
|
0.00
|
0.00
|
0.62 |
0.02
|
0.09 |
0.03
|
0.01
|
0.02
|
0.01
|
0.01
|
0.02
|
0.08 |
1.00 |
0.00
|
0.00
|
|
14K 1.00 |
0.50 |
0.18 |
0.20 |
0.27 |
0.70 |
0.33 |
0.54 |
0.40 |
0.30 |
0.64 |
0.22 |
0.31 |
0.20 |
0.29 |
0.35 |
0.40 |
0.39 |
0.50 |
0.18 |
1.00 |
|
15I 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.16 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.27 |
0.00
|
0.00
|
|
16G 1.00 |
0.22 |
0.01
|
0.65 |
1.00 |
0.02
|
0.25 |
0.08 |
0.02
|
0.22 |
0.05
|
0.02
|
0.30 |
0.13 |
0.25 |
0.07 |
0.20 |
0.12 |
0.05
|
0.01
|
0.04
|
|
17G 1.00 |
0.04
|
0.00
|
0.12 |
0.09 |
0.00
|
1.00 |
0.01
|
0.00
|
0.02
|
0.01
|
0.00
|
0.04
|
0.01
|
0.01
|
0.01
|
0.16 |
0.01
|
0.04
|
0.00
|
0.00
|
|
18Q 1.00 |
0.33 |
0.06 |
0.09 |
0.17 |
0.06 |
0.08 |
0.21 |
0.24 |
0.35 |
0.22 |
0.07 |
0.13 |
0.12 |
1.00 |
0.28 |
0.28 |
0.57 |
0.67 |
0.02
|
0.07 |
|
19L 1.00 |
1.00 |
0.12 |
0.13 |
0.13 |
0.06 |
0.45 |
0.04
|
0.16 |
0.16 |
0.24 |
0.08 |
0.19 |
0.36 |
0.12 |
0.11 |
0.96 |
0.97 |
0.35 |
0.02
|
0.05 |
|
20K 1.00 |
0.18 |
0.06 |
0.01
|
0.03
|
0.04
|
0.01
|
0.01
|
0.60 |
0.22 |
0.23 |
0.06 |
0.02
|
0.04
|
0.02
|
0.02
|
0.03
|
0.14 |
1.00 |
0.01
|
0.02
|
|
21E 1.00 |
0.01
|
0.00
|
0.01
|
1.00 |
0.00
|
0.01
|
0.01
|
0.00
|
0.33 |
0.01
|
0.00
|
0.01
|
0.01
|
0.11 |
0.22 |
0.01
|
0.01
|
0.01
|
0.00
|
0.00
|
|
22A 1.00 |
1.00 |
0.01
|
0.00
|
0.01
|
0.00
|
0.02
|
0.00
|
0.03
|
0.01
|
0.02
|
0.01
|
0.00
|
0.01
|
0.01
|
0.00
|
0.02
|
0.02
|
0.48 |
0.00
|
0.00
|
|
23L 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
24L 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
25D 1.00 |
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
pos |
A |
C |
D |
E |
F |
G |
H |
I |
K |
L |
M |
N |
P |
Q |
R |
S |
T |
V |
W |
Y |
26T 1.00 |
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.13 |
1.00 |
0.00
|
0.00
|
0.00
|
|
27G 1.00 |
0.01
|
0.00
|
0.01
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.01
|
0.01
|
0.00
|
0.04
|
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
|
28A 1.00 |
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.04
|
0.00
|
0.00
|
|
29D 1.00 |
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.04
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
|
30D 1.00 |
0.02
|
0.01
|
1.00 |
0.04
|
0.01
|
0.03
|
0.01
|
0.13 |
0.02
|
0.02
|
0.01
|
0.03
|
0.02
|
0.01
|
0.01
|
0.02
|
0.02
|
0.02
|
0.00
|
0.01
|
|
31T 1.00 |
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.00
|
0.46 |
1.00 |
0.00
|
0.00
|
0.00
|
|
32V 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.02
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.55 |
0.00
|
0.00
|
|
33L 1.00 |
0.01
|
0.00
|
0.00
|
0.00
|
0.21 |
0.00
|
0.00
|
1.00 |
0.00
|
0.91 |
0.02
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.98 |
0.00
|
0.01
|
|
34E 1.00 |
0.77 |
0.04
|
0.44 |
1.00 |
0.04
|
0.29 |
0.09 |
0.13 |
0.76 |
0.21 |
0.07 |
0.41 |
0.19 |
0.46 |
0.37 |
0.61 |
0.44 |
0.20 |
0.01
|
0.03
|
|
35E 1.00 |
0.17 |
0.01
|
0.54 |
1.00 |
0.02
|
0.29 |
0.06 |
0.02
|
0.18 |
0.04
|
0.01
|
0.23 |
0.10 |
0.20 |
0.08 |
0.15 |
0.09 |
0.04
|
0.01
|
0.03
|
|
36M 1.00 |
0.75 |
0.09 |
0.38 |
0.78 |
0.10 |
0.24 |
0.12 |
1.00 |
0.67 |
0.38 |
0.48 |
0.37 |
0.22 |
0.39 |
0.35 |
0.49 |
0.59 |
0.73 |
0.03
|
0.10 |
|
37S 1.00 |
0.07 |
0.00
|
0.96 |
1.00 |
0.01
|
0.05
|
0.02
|
0.01
|
0.30 |
0.02
|
0.01
|
0.63 |
0.03
|
0.25 |
0.04
|
0.35 |
0.05
|
0.02
|
0.00
|
0.01
|
|
38L 1.00 |
0.01
|
0.00
|
0.00
|
0.00
|
0.02
|
0.00
|
0.00
|
0.02
|
0.00
|
1.00 |
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.11 |
0.01
|
|
39P 1.00 |
0.77 |
0.08 |
0.42 |
0.33 |
0.05 |
1.00 |
0.13 |
0.07 |
0.67 |
0.14 |
0.06 |
0.47 |
0.88 |
0.37 |
0.42 |
0.66 |
0.29 |
0.15 |
0.02
|
0.08 |
|
40G 1.00 |
0.11 |
0.02
|
0.39 |
0.13 |
0.02
|
1.00 |
0.06 |
0.02
|
0.13 |
0.03
|
0.01
|
0.37 |
0.28 |
0.08 |
0.10 |
0.45 |
0.33 |
0.03
|
0.01
|
0.03
|
|
41R 1.00 |
0.65 |
0.05
|
0.71 |
0.86 |
0.05 |
0.33 |
0.26 |
0.16 |
1.00 |
0.33 |
0.09 |
0.97 |
0.29 |
0.51 |
0.75 |
0.70 |
0.56 |
0.25 |
0.02
|
0.05
|
|
42W 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.05
|
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.48 |
|
43K 0.95 |
0.28 |
0.05 |
0.20 |
0.30 |
0.13 |
0.16 |
0.13 |
0.12 |
1.00 |
0.19 |
0.07 |
0.18 |
0.11 |
0.34 |
0.43 |
0.49 |
0.50 |
0.21 |
0.04
|
0.18 |
|
44P 1.00 |
0.02
|
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.07 |
0.01
|
0.00
|
0.00
|
0.00
|
|
45K 1.00 |
0.03
|
0.00
|
0.01
|
0.02
|
0.00
|
0.01
|
0.01
|
0.01
|
1.00 |
0.02
|
0.01
|
0.01
|
0.01
|
0.02
|
0.05 |
0.01
|
0.02
|
0.14 |
0.00
|
0.00
|
|
46M 1.00 |
0.01
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
1.00 |
0.00
|
0.08 |
0.75 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.22 |
0.00
|
0.00
|
|
47I 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.02
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.69 |
0.00
|
0.00
|
|
48G 1.00 |
0.01
|
0.00
|
0.02
|
0.01
|
0.00
|
1.00 |
0.12 |
0.00
|
0.01
|
0.00
|
0.00
|
0.03
|
0.01
|
0.01
|
0.01
|
0.02
|
0.01
|
0.00
|
0.00
|
0.00
|
|
49G 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
50I 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
pos |
A |
C |
D |
E |
F |
G |
H |
I |
K |
L |
M |
N |
P |
Q |
R |
S |
T |
V |
W |
Y |
51G 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
52G 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
53F 1.00 |
0.37 |
0.06 |
0.84 |
0.26 |
0.28 |
0.79 |
0.19 |
0.04
|
0.26 |
0.08 |
0.03
|
1.00 |
0.19 |
0.17 |
0.14 |
0.55 |
0.22 |
0.07 |
0.02
|
0.11 |
|
54I 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
1.00 |
0.00
|
0.27 |
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.02
|
0.00
|
0.00
|
|
55K 1.00 |
0.12 |
0.01
|
0.06 |
0.16 |
0.02
|
0.10 |
0.14 |
0.05
|
1.00 |
0.11 |
0.04
|
0.44 |
0.16 |
0.26 |
0.69 |
0.11 |
0.12 |
0.06 |
0.02
|
0.05 |
|
56V 1.00 |
0.06 |
0.01
|
0.00
|
0.01
|
0.01
|
0.00
|
0.00
|
0.07 |
0.01
|
0.05
|
0.17 |
0.01
|
0.01
|
0.01
|
0.01
|
0.01
|
0.50 |
1.00 |
0.00
|
0.00
|
|
57R 1.00 |
0.01
|
0.00
|
0.00
|
0.01
|
0.00
|
0.04
|
0.01
|
0.00
|
1.00 |
0.01
|
0.00
|
0.01
|
0.01
|
0.02
|
0.68 |
0.01
|
0.01
|
0.00
|
0.00
|
0.00
|
|
58Q 1.00 |
0.02
|
0.00
|
0.04
|
1.00 |
0.00
|
0.01
|
0.01
|
0.00
|
0.23 |
0.01
|
0.00
|
0.01
|
0.01
|
0.84 |
0.01
|
0.01
|
0.01
|
0.00
|
0.00
|
0.00
|
|
59Y 1.00 |
0.01
|
0.00
|
0.00
|
0.00
|
0.13 |
0.00
|
0.00
|
0.04
|
0.00
|
0.02
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.12 |
0.00
|
0.01
|
0.02
|
1.00 |
|
60D 1.00 |
0.15 |
0.01
|
1.00 |
0.22 |
0.02
|
0.15 |
0.06 |
0.04
|
0.78 |
0.06 |
0.02
|
0.28 |
0.07 |
0.24 |
0.35 |
0.25 |
0.13 |
0.05 |
0.01
|
0.03
|
|
61Q 1.00 |
0.04
|
0.01
|
0.77 |
0.06 |
0.01
|
0.25 |
0.04
|
0.00
|
0.05 |
0.01
|
0.00
|
1.00 |
0.03
|
0.70 |
0.03
|
0.10 |
0.04
|
0.01
|
0.00
|
0.02
|
|
62I 1.00 |
0.01
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.92 |
0.00
|
0.07 |
0.01
|
0.00
|
0.00
|
0.00
|
0.12 |
0.00
|
0.01
|
1.00 |
0.00
|
0.01
|
|
63L 1.00 |
0.72 |
0.17 |
0.46 |
1.00 |
0.63 |
0.43 |
0.56 |
0.41 |
0.87 |
0.78 |
0.24 |
0.45 |
0.34 |
0.59 |
0.71 |
0.59 |
0.56 |
0.54 |
0.17 |
0.92 |
|
64I 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.10 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.51 |
0.00
|
0.00
|
|
65E 1.00 |
0.10 |
0.01
|
0.18 |
1.00 |
0.01
|
0.22 |
0.02
|
0.02
|
0.37 |
0.04
|
0.01
|
0.07 |
0.05
|
0.24 |
0.19 |
0.08 |
0.07 |
0.03
|
0.00
|
0.01
|
|
66I 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
1.00 |
0.00
|
0.30 |
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.91 |
0.00
|
0.00
|
|
67C 1.00 |
0.39 |
0.09 |
0.04
|
0.09 |
0.15 |
0.03
|
0.05 |
0.67 |
0.09 |
0.70 |
0.17 |
0.05 |
0.09 |
0.07 |
0.07 |
0.09 |
0.28 |
1.00 |
0.03
|
0.08 |
|
68G 1.00 |
0.02
|
0.00
|
0.35 |
0.02
|
0.00
|
1.00 |
0.02
|
0.00
|
0.02
|
0.00
|
0.00
|
0.50 |
0.01
|
0.02
|
0.01
|
0.04
|
0.02
|
0.00
|
0.00
|
0.01
|
|
69H 1.00 |
0.03
|
0.00
|
0.01
|
0.05
|
0.01
|
0.02
|
0.34 |
0.01
|
1.00 |
0.03
|
0.01
|
0.03
|
0.03
|
0.10 |
0.39 |
0.03
|
0.04
|
0.02
|
0.01
|
0.04
|
|
70K 1.00 |
0.17 |
0.02
|
0.05
|
0.22 |
0.06 |
0.13 |
0.13 |
0.19 |
1.00 |
0.20 |
0.08 |
0.15 |
0.12 |
0.33 |
0.81 |
0.14 |
0.17 |
0.18 |
0.03
|
0.09 |
|
71A 1.00 |
0.65 |
0.03
|
0.01
|
0.02
|
0.02
|
0.00
|
0.00
|
0.44 |
0.02
|
0.32 |
0.03
|
0.01
|
0.03
|
0.01
|
0.01
|
0.02
|
0.26 |
1.00 |
0.00
|
0.01
|
|
72I 1.00 |
0.39 |
0.10 |
0.09 |
0.17 |
0.29 |
0.14 |
0.20 |
0.79 |
0.35 |
0.61 |
0.16 |
0.15 |
0.13 |
0.19 |
0.33 |
0.19 |
0.31 |
1.00 |
0.07 |
0.34 |
|
73G 1.00 |
0.33 |
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.03
|
0.02
|
0.01
|
0.01
|
0.00
|
0.00
|
|
74T 1.00 |
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.00
|
0.20 |
1.00 |
0.00
|
0.00
|
0.00
|
|
75V 0.95 |
0.05 |
0.03
|
0.03
|
0.03
|
0.07 |
0.04
|
0.06 |
1.00 |
0.03
|
0.06 |
0.03
|
0.04
|
0.03
|
0.04
|
0.04
|
0.04
|
0.04
|
1.00 |
0.03
|
0.09 |
pos |
A |
C |
D |
E |
F |
G |
H |
I |
K |
L |
M |
N |
P |
Q |
R |
S |
T |
V |
W |
Y |
76L 0.95 |
0.04
|
0.02
|
0.02
|
0.02
|
0.05
|
0.03
|
0.04
|
0.03
|
0.02
|
1.00 |
0.52 |
0.03
|
0.02
|
0.02
|
0.03
|
0.03
|
0.03
|
0.04
|
0.02
|
0.06 |
|
77V 0.95 |
0.15 |
0.06 |
0.07 |
0.09 |
0.20 |
0.10 |
0.16 |
0.63 |
0.09 |
0.27 |
0.07 |
0.10 |
0.07 |
0.09 |
0.11 |
0.12 |
0.87 |
1.00 |
0.06 |
0.28 |
|
78G 0.95 |
0.02
|
0.01
|
0.01
|
0.01
|
0.02
|
1.00 |
0.02
|
0.02
|
0.01
|
0.02
|
0.01
|
0.01
|
0.01
|
0.01
|
0.02
|
0.02
|
0.02
|
0.02
|
0.01
|
0.03
|
|
79P 0.95 |
0.47 |
0.10 |
0.80 |
0.23 |
0.34 |
0.20 |
0.27 |
0.21 |
0.23 |
0.34 |
0.12 |
0.20 |
1.00 |
0.20 |
0.22 |
0.46 |
0.25 |
0.27 |
0.10 |
0.47 |
|
80T 0.95 |
0.02
|
0.01
|
0.01
|
0.01
|
0.02
|
0.01
|
0.02
|
0.02
|
0.01
|
0.02
|
0.01
|
0.01
|
0.01
|
0.01
|
0.01
|
0.02
|
1.00 |
0.02
|
0.01
|
0.03
|
|
81P 0.95 |
0.02
|
0.01
|
0.01
|
0.01
|
0.02
|
0.01
|
0.02
|
0.02
|
0.01
|
0.02
|
0.01
|
0.01
|
1.00 |
0.01
|
0.02
|
0.02
|
0.02
|
0.02
|
0.01
|
0.03
|
|
82V 0.95 |
0.04
|
0.02
|
0.02
|
0.03
|
0.05 |
0.03
|
0.04
|
1.00 |
0.03
|
0.05
|
0.02
|
0.03
|
0.02
|
0.03
|
0.03
|
0.03
|
0.03
|
0.65 |
0.02
|
0.07 |
|
83N 0.95 |
0.02
|
0.01
|
0.10 |
0.02
|
0.03
|
0.02
|
0.02
|
0.02
|
0.02
|
0.03
|
0.01
|
1.00 |
0.01
|
0.02
|
0.02
|
0.02
|
0.02
|
0.02
|
0.01
|
0.04
|
|
84I 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
85I 1.00 |
0.01
|
0.00
|
0.00
|
0.00
|
0.52 |
0.00
|
0.00
|
1.00 |
0.00
|
0.34 |
0.04
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.01
|
0.05
|
0.01
|
0.01
|
|
86G 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
87R 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
88N 1.00 |
0.00
|
0.00
|
0.13 |
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.00
|
0.00
|
|
89L 1.00 |
0.02
|
0.20 |
0.00
|
0.01
|
0.12 |
0.00
|
0.00
|
0.90 |
0.01
|
1.00 |
0.12 |
0.00
|
0.01
|
0.01
|
0.01
|
0.01
|
0.01
|
0.16 |
0.01
|
0.01
|
|
90L 1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
0.01
|
0.00
|
1.00 |
0.08 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.01
|
0.00
|
0.00
|
|
91T 0.97 |
0.29 |
0.01
|
0.07 |
0.23 |
0.00
|
0.03
|
0.01
|
0.01
|
0.05
|
0.02
|
0.01
|
0.09 |
0.02
|
0.20 |
0.03
|
0.07 |
1.00 |
0.02
|
0.00
|
0.01
|
|
92Q 0.97 |
1.00 |
0.08 |
0.36 |
0.58 |
0.05 |
0.52 |
0.10 |
0.12 |
0.73 |
0.21 |
0.08 |
0.31 |
0.29 |
0.62 |
0.46 |
0.62 |
0.44 |
0.22 |
0.02
|
0.05 |
|
93I 0.97 |
0.22 |
0.00
|
0.00
|
0.00
|
0.04
|
0.00
|
0.00
|
0.49 |
0.01
|
1.00 |
0.12 |
0.00
|
0.01
|
0.01
|
0.01
|
0.00
|
0.01
|
0.05 |
0.00
|
0.01
|
|
94G 0.97 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
95C 0.97 |
1.00 |
0.15 |
0.07 |
0.09 |
0.11 |
0.53 |
0.03
|
0.16 |
0.10 |
0.46 |
0.17 |
0.07 |
0.24 |
0.08 |
0.08 |
0.48 |
0.18 |
0.22 |
0.02
|
0.06 |
|
96T 0.97 |
0.12 |
0.02
|
0.05
|
0.08 |
0.02
|
0.06 |
0.05
|
0.04
|
0.65 |
0.06 |
0.03
|
0.10 |
0.07 |
0.12 |
0.43 |
0.73 |
1.00 |
0.06 |
0.01
|
0.03
|
|
97L 0.97 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
|
98N 0.82 |
0.03
|
0.00
|
0.03
|
0.01
|
0.00
|
0.03
|
0.01
|
0.01
|
0.01
|
0.01
|
0.00
|
1.00 |
0.01
|
0.01
|
0.01
|
0.03
|
0.02
|
0.08 |
0.00
|
0.00
|
|
99F 0.50 |
0.00
|
0.00
|
0.00
|
0.00
|
1.00 |
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|
0.00
|